Acid Phosphatase
Naphtylphosphate substrate
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Product description:
Acid phosphatase is a ubiquitous lysosomal enzyme that hydrolyses organic phosphates at an acid
pH. Acid phosphatases are a group of five ubiquitous tissue isoenzymes that hydrolyze organic
monophosphate esters. They are present in many human tissues including platelets, lung,
osteoclasts, erythrocytes, liver, and kidney. However, prostate-specific acid phosphatase is
over 100 times more abundant in the prostate than in other tissue types. In clinical chemistry
the measurement of acid phosphatase is used almost exclusively in the diagnosis and control of
therapy of prostatic carcinoma. In hematological disorders, bones or liver diseases as well as
in Paget's disease, the activity of the enzyme is also increased.
